BHMT antibody (AA 1-406)

Catalog No. ABIN7596087

This Mouse Monoclonal antibody specifically detects BHMT in WB, ELISA, IF, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for BHMT antibody (AA 1-406) (ABIN7596087)

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BHMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3D6

Product Details anti-BHMT Antibody

Binding Specificity: AA 1-406

Purpose: Human BHMT antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human BHMT (1-406aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for BHMT

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Alternative Name: BHMT

Background: Betaine homocysteine methyltransferase (BHMT), a cytosolic enzyme, and its partial fragments were discovered as autolysosomal membrane proteins from rat liver in the presence of leupeptin. BHMT was also found in human liver. BHMT transfers a methyl group from betaine to homocysteine to form DMG (dimethylglycine) and Met. In vivo, liver BHMT expression is influenced by dietary changes in sulphur amino acids, choline and betaine.

NCBI Accession: NP_001704

Pathways: Methionine Biosynthetic Process