BHMT antibody (C-Term)

Catalog No. ABIN2776836

The Rabbit Polyclonal anti-BHMT antibody (ABIN2776836) specifically detects BHMT in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit and Pig samples.

Quick Overview for BHMT antibody (C-Term) (ABIN2776836)

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BHMT Antibody

Binding Specificity: C-Term

Purpose: BHMT Antibody - C-terminal region

Sequence: KHGSWGSGLD MHTKPWVRAR ARKEYWENLR IASGRPYNPS MSKPDGWGVT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against BHMT. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BHMT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095543

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BHMT

Target: BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

Alternative Name: BHMT

Background:

Background Information: BHMT is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in its gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.Betaine-homocysteine methyltransferase is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in BHMT could lead to hyperhomocyst(e)inemia,but such a defect has not yet been observed.

Gene Name: Betaine--homocysteine S-methyltransferase

Alternative Symbols: BHMT1, HEL-S-61p

Protein Name: Betaine--homocysteine S-methyltransferase 1

Molecular Weight: 45kDa

Gene ID: 635

NCBI Accession: NP_001704

UniProt: Q93088

Pathways: Methionine Biosynthetic Process