TREM2 antibody (AA 19-161)

Catalog No. ABIN7596109

The Mouse Monoclonal anti-TREM2 antibody has been validated for WB, ELISA, FACS, ICC and IF. It is suitable to detect TREM2 in samples from Human.

Quick Overview for TREM2 antibody (AA 19-161) (ABIN7596109)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT1E7

Product Details anti-TREM2 Antibody

Binding Specificity: AA 19-161

Purpose: Human TREM2 antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human TREM2 (19-161aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background: The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).

NCBI Accession: NP_061838