Annexin V antibody (Internal Region)

Catalog No. ABIN7598805

This Rabbit Monoclonal antibody specifically detects Annexin V in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Annexin V antibody (Internal Region) (ABIN7598805)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Annexin V antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: N23-I

Product Details anti-Annexin V Antibody

Binding Specificity: AA 149-166, Internal Region

Purpose: Anti-Annexin A5

Specificity: Annexin A1

Immunogen: Peptide derived from the internal region of human Annexin A1. Antibody recognizes the epitope between Ile149 - Lys166.

Isotype: IgG

Application Details

Application Notes: Ready to use antibody dilution. Directly use for application

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: +4˚C, Do not freeze!

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: Annexin A5

Background: Annexin A1 (ANXA1) is a phospholipid-binding protein belonging to the annexin family. It plays a key role in the regulation of inflammation, apoptosis, cell proliferation, and membrane stability. In immunohistochemistry, Annexin A1 is used as a marker in various inflammatory, autoimmune, and neoplastic conditions. Altered expression of Annexin A1 has been observed in several cancer types, including colorectal cancer, breast carcinoma, and certain leukemias. Its expression can be associated with tumor differentiation, response to therapy, and prognosis in pathological assessment.

UniProt: P04083

Pathways: Apoptosis