NRAP antibody (AA 1-1513)

Catalog No. ABIN7599006

Product Details anti-NRAP Antibody

Target: NRAP (Nebulin Related Anchoring Protein (NRAP))

Binding Specificity: AA 1-1513

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRAP antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Anti-NRAP Antibody Picoband®

Characteristics: Anti-NRAP Antibody Picoband® (ABIN7599006). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NRAP recombinant protein (Position: M1-K1513). Human NRAP shares 86.8% amino acid (aa) sequence identity with mouse NRAP.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Luo, G., Leroy, E., Kozak, C. A., Polymeropoulos, M. H., Horowits, R. Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics 45: 229-232, 1997. 2. Luo, G., Zhang, J. Q., Nguyen, T.-P., Herrera, A. H., Paterson, B., Horowits, R. Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle. Cell Motil. Cytoskeleton 38: 75-90, 1997. 3. Truszkowska, G. T., Bilinska, Z. T., Muchowicz, A., Pollak, A., Biernacka, A., Kozar-Kaminska, K., Stawinski, P., Gasperowicz, P., Kosinska, J., Zielinski, T., Ploski, R. Homozygous truncating mutation in NRAP gene identified by whole exome sequencing in a patient with dilated cardiomyopathy. Sci. Rep. 7: 3362, 2017. Note: Electronic Article.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NRAP

Target: NRAP (Nebulin Related Anchoring Protein (NRAP))

Alternative Name: NRAP (NRAP Products)

Background: NRAP may be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix.

Molecular Weight: 250 kDa

Gene ID: 4892