CUX1 antibody (AA 1-220)

Catalog No. ABIN7599103

This Rabbit Polyclonal antibody specifically detects CUX1 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for CUX1 antibody (AA 1-220) (ABIN7599103)

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CUX1 Antibody

Binding Specificity: AA 1-220

Purpose: Anti-CUX1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CUX1 Antibody Picoband® (ABIN7599103). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CUX1 recombinant protein (Position: M1-E220).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cubelos, B., Sebastian-Serrano, A., Beccari, L., Calcagnotto, M. E., Cisneros, E., Kim, S., Dopazo, A., Alvarez-Dolado, M., Redondo, J. M., Bovolenta, P., Walsh, C. A., Nieto, M. Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron 66: 523-535, 2010. 2. Doan, R. N., Bae, B.-I., Cubelos, B., Chang, C., Hossain, A. A., Al-Saad, S., Mukaddes, N. M., Oner, O., Al-Saffar, M., Balkhy, S., Gascon G. G., The Homozygosity Mapping Consortium for Autism, Nieto, M., Walsh, C. A. Mutations in human accelerated regions disrupt cognition and social behavior. Cell 167: 341-354, 2016. 3. Gillingham, A. K., Pfeifer, A. C., Munro, S. CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin. Molec. Biol. Cell. 13: 3761-3774, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1

Background:

Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).

Background: The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 200 kDa

Gene ID: 1523

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process