EGR2 antibody (AA 1-257)

Catalog No. ABIN7599174

This anti-EGR2 antibody is a Rabbit Polyclonal antibody detecting EGR2 in WB, ELISA and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for EGR2 antibody (AA 1-257) (ABIN7599174)

Target: EGR2 (Early Growth Response 2 (EGR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-EGR2 Antibody

Binding Specificity: AA 1-257

Purpose: Anti-EGR2 Antibody Picoband®

Characteristics: Anti-EGR2 Antibody Picoband® (ABIN7599174). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EGR2 recombinant protein (Position: M1-R257). Human EGR2 shares 90.7% amino acid (aa) sequence identity with both mouse and rat EGR2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boerkoel, C. F., Takashima, H., Bacino, C. A., Daentl, D., Lupski, J. R. EGR2 mutation R359W causes a spectrum of Dejerine-Sottas neuropathy. Neurogenetics 3: 153-157, 2001. 2. Chavrier, P., Janssen-Timmen, U., Mattei, M.-G., Zerial, M., Bravo, R., Charnay, P. Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos. Molec. Cell. Biol. 9: 787-797, 1989. 3. Chung, K. W., Sunwoo, I. N., Kim, S. M., Park, K. D., Kim, W.-K., Kim, T. S., Koo, H., Cho, M., Lee, J., Choi, B. O. Two missense mutations of EGR2 R359W and GJB1 V136A in a Charcot-Marie-Tooth disease family. Neurogenetics 6: 159-163, 2005.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Alternative Name: EGR2

Background: Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 50 kDa

Gene ID: 1959

UniProt: P11161