OLIG1 antibody (AA 1-271)

Catalog No. ABIN7599193

This Rabbit Polyclonal antibody specifically detects OLIG1 in WB, ELISA and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OLIG1 antibody (AA 1-271) (ABIN7599193)

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLIG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-OLIG1 Antibody

Binding Specificity: AA 1-271

Purpose: Anti-Olig1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Olig1 Antibody Picoband® (ABIN7599193). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Olig1 recombinant protein (Position: M1-K271).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arnett, H. A., Fancy, S. P. J., Alberta, J. A., Zhao, C., Plant, S. R., Kaing, S., Raine, C. S., Rowitch, D. H., Franklin, R. J. M., Stiles, C. D. bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science 306: 2111-2115, 2004. 2. Lu, Q. R., Sun, T., Zhu, Z., Ma, N., Garcia, M., Stiles, C. D., Rowitch, D. H. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 109: 75-86, 2002. 3. Zhou, Q., Anderson, D. J. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 109: 61-73, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for OLIG1

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Alternative Name: OLIG1

Background:

Synonyms: Cyclin-dependent kinase 16 (EC:2.7.11.22), Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1, CDK16, PCTAIRE1, PCTK1

Tissue Specificity: Detected in pancreas islets (at protein level). Detected in brain and pancreas.

Background: Oligodendrocyte transcription factor 1 (OLIG1), also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. OLIG1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Molecular Weight: 28 kDa

Gene ID: 116448