TPI1 antibody (AA 1-286)

Catalog No. ABIN7599216

This anti-TPI1 antibody is a Rabbit Polyclonal antibody detecting TPI1 in WB, ELISA and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for TPI1 antibody (AA 1-286) (ABIN7599216)

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TPI1 Antibody

Binding Specificity: AA 1-286

Purpose: Anti-TPI1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TPI1 Antibody Picoband® (ABIN7599216). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TPI1 recombinant protein (Position: M1-Q286).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arya, R., Lalloz, M. R. A., Bellingham, A. J., Layton, D. M. Evidence for founder effect of the glu104-to-asp substitution and identification of new mutations in triosephosphate isomerase deficiency. Hum. Mutat. 10: 290-294, 1997. 2. Asakawa, J., Iida, S. Origin of human triosephosphate isomerase isozymes: further evidence for the single structural locus hypothesis with Japanese variants. Hum. Genet. 71: 22-26, 1985. 3. Asakawa, J., Satoh, C., Takahashi, N., Fujita, M., Kaneko, J., Goriki, K., Hazama, R., Kageoka, T. Electrophoretic variants of blood proteins in Japanese: III. Triosephosphate isomerase. Hum. Genet. 68: 185-188, 1984.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TPI1

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Alternative Name: TPI1

Background:

Synonyms: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1l

Tissue Specificity: Macrophages, peripheral blood leukocytes, lung, spleen and liver.

Background: Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Molecular Weight: 27 kDa

Gene ID: 7167

UniProt: P60174

Pathways: Cell RedoxHomeostasis