serine Dehydratase antibody (AA 1-328)

Catalog No. ABIN7599277

This Rabbit Polyclonal antibody specifically detects serine Dehydratase in WB, FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for serine Dehydratase antibody (AA 1-328) (ABIN7599277)

Target: serine Dehydratase (SDS)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This serine Dehydratase antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-serine Dehydratase Antibody

Binding Specificity: AA 1-328

Purpose: Anti-SDS Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SDS Antibody Picoband® (ABIN7599277). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SDS recombinant protein (Position: M1-K328).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ogawa, H., Gomi, T., Konishi, K., Date, T., Nakashima, H., Nose, K., Matsuda, Y., Peraino, C., Pitot, H. C., Fujioka, M. Human liver serine dehydratase: cDNA cloning and sequence homology with hydroxyamino acid dehydratases from other sources. J. Biol. Chem. 264: 15818-15823, 1989. [PubMed: 2674117, related citations] [Full Ogawa, H., Gomi, T., Konishi, K., Date, T., Nakashima, H., Nose, K., Matsuda, Y., Peraino, C., Pitot, H. C., Fujioka, M. Human liver serine dehydratase: cDNA cloning and sequence homology with hydroxyamino acid dehydratases from other sources. J. Biol. Chem. 264: 15818-15823, 1989.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for serine Dehydratase

Target: serine Dehydratase (SDS)

Alternative Name: SDS

Background:

Synonyms: Mitochondrial uncoupling protein 2,UCP 2,Solute carrier family 25 member 8,UCPH,UCP2,SLC25A8,

Tissue Specificity: Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle.

Background: Serine dehydratase or L-serine ammonia lyase (SDH) is in the β-family of pyridoxal phosphate-dependent (PLP) enzymes. This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.

Molecular Weight: 42 kDa

Gene ID: 10993

UniProt: P20132

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly