SOX17 antibody (AA 1-414)

Catalog No. ABIN7599367

This Rabbit Polyclonal antibody specifically detects SOX17 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for SOX17 antibody (AA 1-414) (ABIN7599367)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOX17 Antibody

Binding Specificity: AA 1-414

Purpose: Anti-SOX17 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SOX17 Antibody Picoband® (ABIN7599367). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOX17 recombinant protein (Position: M1-V414).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gimelli, S., Caridi, G., Beri, S., McCracken, K., Bocciardi, R., Zordan, P., Dagnino, M., Fiorio, P., Murer, L., Benetti, E., Zuffardi, O., Giorda, R., Wells, J. M., Gimelli, G., Ghiggeri, G. M. Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract. Hum. Mutat. 31: 1352-1359, 2010. 2. Heidet, L., Moriniere, V., Henry, C., De Tomasi, L., Reilly, M. L., Humbert, C., Alibeu, O., Fourrage, C., Bole-Feysot, C., Nitschke, P., Tores, F., Bras, M., and 13 others. Targeted exome sequencing identifies PBX1 as involved in monogenic congenital anomalies of the kidney and urinary tract. J. Am. Soc. Nephrol. 28: 2901-2914, 2017. 3. Kanai, Y., Kanai-Azuma, M., Noce, T., Saido, T. C., Shiroishi, T., Hayashi, Y., Yazaki, K. Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis. J. Cell Biol. 133: 667-681, 1996.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17

Background:

Synonyms: Deoxycytidine kinase, dCK, DCK,

Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).

Background: SRY-box 17 is a protein that in humans is encoded by the SOX17 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Molecular Weight: 45 kDa

Gene ID: 64321

UniProt: Q9H6I2