OXER1 antibody (AA 1-422)

Catalog No. ABIN7599381

This anti-OXER1 antibody is a Rabbit Polyclonal antibody detecting OXER1 in ELISA, WB and FACS. Suitable for Human.

Quick Overview for OXER1 antibody (AA 1-422) (ABIN7599381)

Target: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXER1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-OXER1 Antibody

Binding Specificity: AA 1-422

Purpose: Anti-OXER1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-OXER1 Antibody Picoband® (ABIN7599381). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OXER1 recombinant protein (Position: M1-Q422).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dattilo, M., Neuman, I., Munoz, M., Maloberti, P., Cornejo Maciel, F. OxeR1 regulates angiotensin II and cAMP-stimulated steroid production in human H295R adrenocortical cells. Molec. Cell. Endocr. 408: 38-44, 2015 2. Enyedi, B., Kala, S., Nikolich-Zugich, T., Niethammer, P. Tissue damage detection by osmotic surveillance. Nature Cell Biol. 15: 1123-1130, 2013. 3. Hosoi, T., Koguchi, Y., Sugikawa, E., Chikada, A., Ogawa, K., Tsuda, N., Suto, N., Tsunoda, S., Taniguchi, T., Ohnuki, T. Identification of a novel human eicosanoid receptor coupled to G(i/o). J. Biol. Chem. 277: 31459-31465, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for OXER1

Target: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Alternative Name: OXER1

Background:

Synonyms: E3 ubiquitin-protein ligase RNF169, RING finger protein 169, RING-type E3 ubiquitin transferase RNF169, RNF169, KIAA1991

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Oxoeicosanoid receptor 1 (OXER1) also known as G-protein coupled receptor 170 (GPR170) is a protein that in humans is encoded by the OXER1 gene located on human chromosome 2p21, it is the principal receptor for the 5-Hydroxyicosatetraenoic acid family of carboxy fatty acid metabolites derived from arachidonic acid. Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane.

Molecular Weight: 43-46 kDa

Gene ID: 165140

Pathways: cAMP Metabolic Process