OXER1 antibody (AA 180-260)

Catalog No. ABIN7217292

The Rabbit Polyclonal anti-OXER1 antibody (ABIN7217292) specifically detects OXER1 in ELISA, WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for OXER1 antibody (AA 180-260) (ABIN7217292)

Target: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXER1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-OXER1 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-TG1019 Polyclonal Antibody

Specificity: TG1019 Polyclonal Antibody detects endogenous levels of TG1019 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TG1019 at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OXER1

Target: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Alternative Name: TG1019

Background: OXER1, GPR170, TG1019, Oxoeicosanoid receptor 1, 5-oxo-ETE G-protein coupled receptor, G-protein coupled receptor 170, G-protein coupled receptor R527, G-protein coupled receptor TG1019OXER1 (Oxoeicosanoid (OXE) Receptor 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding. An important paralog of this gene is HCAR3. Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4, LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase enzymes. They are important in inflammatory signaling pathways.

Molecular Weight: 46kD

Gene ID: 165140

UniProt: Q8TDS5

Pathways: cAMP Metabolic Process