GNG4 antibody (AA 1-52)

Catalog No. ABIN7599461

The Rabbit Polyclonal anti-GNG4 antibody has been validated for ELISA, WB, IHC and FACS. It is suitable to detect GNG4 in samples from Human, Mouse and Rat.

Quick Overview for GNG4 antibody (AA 1-52) (ABIN7599461)

Target: GNG4 (G Protein gamma 4 (GNG4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNG4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-GNG4 Antibody

Binding Specificity: AA 1-52

Purpose: Anti-GNG4 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-GNG4 Antibody Picoband® (ABIN7599461). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GNG4 recombinant protein (Position: M1-D52).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahmad, W., Li, S., Chen, H., Tuck-Muller, C. M., Pittler, S. J., Aronson, N. N., Jr. Lysosomal chitobiase (CTB) and the G-protein gamma-5 subunit (GNG5) genes co-localize to human chromosome 1p22. Cytogenet. Cell Genet. 71: 44-46, 1995. 2. Gilman, A. G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56: 615-649, 1987. 3. Ray, K., Kunsch, C., Bonner, L. M., Robishaw, J. D. Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma-4, gamma-10, and gamma-11 subunits. J. Biol. Chem. 270: 21765-21771, 1995.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for GNG4

Target: GNG4 (G Protein gamma 4 (GNG4))

Alternative Name: GNG4

Background:

Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

Background: Guanine nucleotide-binding protein G (I)/G (S)/G (O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene. This gene encodes the gamma subunit of the heterotrimeric G-proteins that are comprised of alpha, beta and gamma subunits. Upon activation by G protein-coupled receptors, the beta-gamma heterodimer dissociates from the alpha subunit to activate downstream signaling events. Alternate splicing results in multiple transcript variants.

Molecular Weight: 12 kDa

Gene ID: 2786

UniProt: P50150

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling