PLSCR1 antibody (AA 1-54)

Catalog No. ABIN7599471

This anti-PLSCR1 antibody is a Rabbit Polyclonal antibody detecting PLSCR1 in WB, IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for PLSCR1 antibody (AA 1-54) (ABIN7599471)

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLSCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLSCR1 Antibody

Binding Specificity: AA 1-54

Purpose: Anti-Scramblase 1/PLSCR1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Scramblase 1/PLSCR1 Antibody Picoband® (ABIN7599471). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Scramblase 1/PLSCR1 recombinant protein (Position: M1-S54).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Basse, F., Stout, J. G., Sims, P. J., Wiedmer, T. Isolation of an erythrocyte membrane protein that mediates Ca(2+)-dependent transbilayer movement of phospholipid. J. Biol. Chem. 271: 17205-17210, 1996. 2. Kametaka, S., Shibata, M., Moroe, K., Kanamori, S., Ohsawa, Y., Waguri, S., Sims, P. J., Emoto, K., Umeda, M., Uchiyama, Y. Identification of phospholipid scramblase 1 as a novel interacting molecule with beta-secretase (beta-site amyloid precursor protein (APP) cleaving enzyme (BACE). J. Biol. Chem. 278: 15239-15245, 2003. 3. Kasukabe, T., Kobayashi, H., Kaneko, Y., Okabe-Kado, J., Honma, Y. Identity of human normal counterpart (MmTRA1b) of mouse leukemogenesis-associated gene (MmTRA1a) product as a plasma membrane phospholipid scramblase and chromosome mapping of the human MmTRA1b/phospholipid scramblase gene. Biochem. Biophys. Res. Commun. 249: 449-455, 1998.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PLSCR1

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Alternative Name: PLSCR1

Background:

Synonyms: Phospholipid scramblase 1, PL scramblase 1, Ca (2+)-dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase, MmTRA1b, PLSCR1

Tissue Specificity: Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.

Background: Phospholipid scramblase 1 is a protein that in human is encoded by the PLSCR1 gene. This gene is mapped to 3q24.

Molecular Weight: 35 kDa

Gene ID: 5359

UniProt: O15162

Pathways: Cellular Response to Molecule of Bacterial Origin