SLC6A17 antibody (AA 1-694)

Catalog No. ABIN7599527

Product Details anti-SLC6A17 Antibody

Target: SLC6A17 (Solute Carrier Family 6, Member 17 (SLC6A17))

Binding Specificity: AA 1-694

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-SLC6A17 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SLC6A17 Antibody Picoband® (ABIN7599527). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SLC6A17 recombinant protein (Position: M1-Y694).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hoglund, P. J., Adzic, D., Scicluna, S. J., Lindblom, J., Fredriksson, R. The repertoire of solute carriers of family 6: identification of new human and rodent genes. Biochem. Biophys. Res. Commun. 336: 175-189, 2005. 2. Iqbal, Z., Willemsen, M. H., Papon, M.-A., Musante, L., Benevento, M., Hu, H., Venselaar, H., Wissink-Lindhout, W. M., Vulto-van Silfhout, A. T., Vissers, L. E. L. M., de Brouwer, A. P. M., Marouillat, S., Wienker, T. F., Ropers, H. H., Kahrizi, K., Nadif Kasri, N., Najmabadi, H., Laumonnier, F., Kleefstra, T., van Bokhoven, H. Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems. Am. J. Hum. Genet. 96: 386-396, 2015.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SLC6A17

Target: SLC6A17 (Solute Carrier Family 6, Member 17 (SLC6A17))

Alternative Name: SLC6A17 (SLC6A17 Products)

Background:

Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Background: The protein encoded by this gene is a member of the SLC6 family of transporters, which are responsible for the presynaptic uptake of most neurotransmitters. The encoded vesicular transporter is selective for proline, glycine, leucine and alanine. In mouse, the strongest expression of this gene was in cortical and hippocampal tissues where expression increased during embryonic brain development and peaked postnatally. Defects in this gene cause a form of autosomal recessive intellectual disability.

Molecular Weight: 81 kDa

Gene ID: 388662

UniProt: Q9H1V8