PKIB antibody (AA 1-78)

Catalog No. ABIN7599546

Product Details anti-PKIB Antibody

Target: PKIB (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor beta (PKIB))

Binding Specificity: AA 1-78

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKIB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purpose: Anti-PKIB Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PKIB Antibody Picoband® (ABIN7599546). Tested in ELISA, IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PKIB recombinant protein (Position: M1-K78).

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Van Patten, S. M., Ng, D. C., Th'ng, J. P. H., Angelos, K. L., Smith, A. J., Walsh, D. A. Molecular cloning of a rat testis form of the inhibitor protein of cAMP-dependent protein kinase. Proc. Nat. Acad. Sci. 88: 5383-5387, 1991.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for PKIB

Target: PKIB (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor beta (PKIB))

Alternative Name: PKIB (PKIB Products)

Background:

Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Background: cAMP-dependent protein kinase inhibitor beta is a protein that in humans is encoded by the PKIB gene. This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 110 kDa

Gene ID: 5570

UniProt: Q9C010

Pathways: Myometrial Relaxation and Contraction