SNRNP27 antibody (AA 100-155)

Catalog No. ABIN7599614

Product Details anti-SNRNP27 Antibody

Target: SNRNP27 (Small Nuclear Ribonucleoprotein 27kDa (U4/U6.U5) (SNRNP27))

Binding Specificity: AA 100-155

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP27 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Anti-SNRNP27 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SNRNP27 Antibody Picoband® (ABIN7599614). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SNRNP27 recombinant protein (Position: E100-A155).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Fetzer, S., Lauber, J., Will, C. L., Luhrmann, R. The [U4/U6.U5] tri-snRNP-specific 27K protein is a novel SR protein that can be phosphorylated by the snRNP-associated protein kinase. RNA 3: 344-355, 1997. 2. Gross, M. B. Personal Communication. Baltimore, Md. 11/18/2021. 3. Nakamura, Y., Moriuchi, R., Nakayama, D., Yamashita, I., HIgashiyama, Y., Yamamoto, T., Kusano, Y., Hino, S., Miyamoto, T., Katamine, S. Altered expression of a novel cellular gene as a consequence of integration of human T cell lymphotropic virus type 1. J. Gen. Virol. 75: 2625-2633, 1994.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SNRNP27

Target: SNRNP27 (Small Nuclear Ribonucleoprotein 27kDa (U4/U6.U5) (SNRNP27))

Alternative Name: SNRNP27 (SNRNP27 Products)

Background:

Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

Background: This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 23 kDa

Gene ID: 11017