PTH1R antibody (AA 102-446)
Quick Overview for PTH1R antibody (AA 102-446) (ABIN7599639)
Target
See all PTH1R AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 102-446
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Purpose
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody (ABIN7599639). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Parathyroid Hormone Receptor 1/PTH1R recombinant protein (Position: R102-L446).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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Alternative Name
- PTH1R
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Background
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Synonyms: Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, p47-phox, NCF1, NOXO2, SH3PXD1A
Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level).
Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
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Molecular Weight
- 66 kDa
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Gene ID
- 5745
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UniProt
- Q03431
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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