LLGL2 antibody (AA 102-553)

Catalog No. ABIN7599642

This anti-LLGL2 antibody is a Rabbit Polyclonal antibody detecting LLGL2 in WB, ELISA and FACS. Suitable for Human.

Quick Overview for LLGL2 antibody (AA 102-553) (ABIN7599642)

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LLGL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-LLGL2 Antibody

Binding Specificity: AA 102-553

Purpose: Anti-LLGL2 Antibody Picoband®

Characteristics: Anti-LLGL2 Antibody Picoband® (ABIN7599642). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LLGL2 recombinant protein (Position: L102-Q553). Human LLGL2 shares 91.2% amino acid (aa) sequence identity with mouse LLGL2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2019. 2. Saito, Y., Li, L., Coyaud, E., Luna, A., Sander, C., Raught, B., Asara, J. M., Brown, M., Muthuswamy, S. K. LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer. Nature 569: 275-279, 2019. 3. Sripathy, S., Lee, M., Vasioukhin, V. Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development. Molec. Cell. Biol. 31: 2920-2933, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for LLGL2

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: LLGL2

Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 120 kDa

Gene ID: 3993

UniProt: Q6P1M3

Pathways: WNT Signaling