TNNI3K antibody (AA 102-783)

Catalog No. ABIN7599644

The Rabbit Polyclonal anti-TNNI3K antibody has been validated for WB, ELISA and FACS. It is suitable to detect TNNI3K in samples from Human, Mouse and Rat.

Quick Overview for TNNI3K antibody (AA 102-783) (ABIN7599644)

Target: TNNI3K (TNNI3 Interacting Kinase (TNNI3K))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNI3K antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TNNI3K Antibody

Binding Specificity: AA 102-783

Purpose: Anti-TNNI3K Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TNNI3K Antibody Picoband® (ABIN7599644). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TNNI3K recombinant protein (Position: F102-Q783).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fan, L.-L., Huang, H., Jin, J.-Y., Li, J.-J., Chen, Y.-Q., Zhao, S.-P., Xiang, R. Whole exome sequencing identifies a novel mutation (c.333+2T-C) of TNNI3K in a Chinese family with dilated cardiomyopathy and cardiac conduction disease. Gene 648: 63-67, 2018. 2. Lai, Z.-F., Chen, Y.-Z., Feng, L.-P., Meng, X.-M., Ding, J.-F., Wang, L.-Y., Ye, J., Li, P., Cheng, X.-S., Kitamoto, Y., Monzen, K., Komuro, I., Sakaguchi, N., Kim-Mitsuyama, S. Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury. Am. J. Physiol. Heart Circ. Physiol. 295: H708-H716, 2008. Note: Erratum: Am. J. Physiol. Heart Circ. Physiol. 295: H1815 only, 2008. 3. Patterson, M., Barske, L., Van Handel, B., Rau, C. D., Gan, P., Sharma, A., Parikh, S., Denholtz, M., Huang, Y., Yamaguchi, Y., Shen, H., Allayee, H., Crump, J. G., Force, T. I., Lien, C.-L., Makita, T., Lusis, A. J., Kumar, S. R., Sucov, H. M. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genet. 49: 1346-1353, 2017.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TNNI3K

Target: TNNI3K (TNNI3 Interacting Kinase (TNNI3K))

Alternative Name: TNNI3K

Background:

Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD

Background: TNNI3 interacting kinase is a protein that in humans is encoded by the TNNI3K gene. This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Molecular Weight: 110 kDa

Gene ID: 51086

UniProt: Q59H18