Syntaxin 12 antibody (AA 103-245)

Catalog No. ABIN7599647

The Rabbit Polyclonal anti-Syntaxin 12 antibody has been validated for WB, ELISA, IF, FACS and ICC. It is suitable to detect Syntaxin 12 in samples from Human, Mouse and Rat.

Quick Overview for Syntaxin 12 antibody (AA 103-245) (ABIN7599647)

Target: Syntaxin 12 (STX12)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-Syntaxin 12 Antibody

Binding Specificity: AA 103-245

Purpose: Anti-Syntaxin 12/STX12 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-Syntaxin 12/STX12 Antibody Picoband® (ABIN7600936). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Syntaxin 12/STX12 recombinant protein (Position: K103-K245). Human STX12 shares 95.1% and 93.7% amino acid (aa) sequence identity with mouse and rat STX12, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Ambrosio, A. L., Febvre, H. P., Di Pietro, S. M. Syntaxin 12 and COMMD3 are new factors that function with VPS33B in the biogenesis of platelet alpha-granules. Blood 139: 922-935, 2022. 3. Collins, R. F., Schreiber, A. D., Grinstein, S., Trimble, W. S. Syntaxins 13 and 7 function at distinct steps during phagocytosis. J. Immun. 169: 3250-3256, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for Syntaxin 12

Target: Syntaxin 12 (STX12)

Alternative Name: STX12

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Syntaxin-12 is a protein that in humans is encoded by the STX12 gene. STX12 functions with the VPS16B/VPS33B (608552) complex in the biogenesis of platelet alpha-granules.

Molecular Weight: 37 kDa

Gene ID: 23673

UniProt: Q86Y82

Pathways: Synaptic Vesicle Exocytosis