MBNL3 antibody (AA 106-312)

Catalog No. ABIN7599670

This Rabbit Polyclonal antibody specifically detects MBNL3 in ELISA, WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for MBNL3 antibody (AA 106-312) (ABIN7599670)

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-MBNL3 Antibody

Binding Specificity: AA 106-312

Purpose: Anti-MBNL3 Antibody Picoband®

Characteristics: Anti-MBNL3 Antibody Picoband® (ABIN7599670). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MBNL3 recombinant protein (Position: L106-C312).

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fardaei, M., Rogers, M. T., Thorpe, H. M., Larkin, K., Hamshere, M. G., Harper, P. S., Brook, J. D. Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells. Hum. Molec. Genet. 11: 805-814, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/11/2012. 3. Ho, T. H., Charlet-B, N., Poulos, M. G., Singh, G., Swanson, M. S., Cooper, T. A. Muscleblind proteins regulate alternative splicing. EMBO J. 23: 3103-3112, 2004.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MBNL3

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Alternative Name: MBNL3

Background: Muscleblind-like protein 3 is a protein that in humans is encoded by the MBNL3 gene. This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described.

Molecular Weight: 27 kDa

Gene ID: 55796

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development