Uroplakin 1B antibody (AA 107-216)

Catalog No. ABIN7599675

This anti-Uroplakin 1B antibody is a Rabbit Polyclonal antibody detecting Uroplakin 1B in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Uroplakin 1B antibody (AA 107-216) (ABIN7599675)

Target: Uroplakin 1B (UPK1B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 107-216

Purpose: Anti-Uroplakin Ib/UPIb Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Uroplakin Ib/UPIb Antibody Picoband® (ABIN7599675). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Uroplakin Ib/UPIb recombinant protein (Position: I107-Q216).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Finch, J. L., Webb, G. C., Evdokiou, A, Cowled, P. A. Chromosomal localization of the human urothelial tetraspan gene, UPK1B, to 3q13.3-q21 and detection of a Taq1 polymorphism. Genomics 40: 501-503, 1997. 2. Lobban, E. D., Smith, B. A., Hall, G. D., Harnden, P., Roberts, P., Selby, P. J., Trejdosiewicz, L. K., Southgate, J. Uroplakin gene expression by normal and neoplastic human urothelium. Am. J. Path. 153: 1957-1967, 1998. 3. Olsburgh, J., Weeks, R., Selby, P., Southgate, J. Human uroplakin 1b gene structure and promoter analysis. Biochim. Biophys. Acta 1576: 163-170, 2002. 4. Webb, G. C., Finch, J. L., Cowled, P. A. Assignment of the uroplakin 1b (Upk1b) gene to mouse chromosome 16 bands B5-C2 by in situ hybridization. Cytogenet. Cell Genet. 84: 37-38, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B

Background:

Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,

Tissue Specificity: Ubiquitous. Highly expressed in brain. .

Background: Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

Molecular Weight: 30 kDa

Gene ID: 7348

UniProt: O75841