Uroplakin 1B antibody (Middle Region)

Catalog No. ABIN955480

Product Details anti-Uroplakin 1B Antibody

Target: Uroplakin 1B (UPK1B)

Binding Specificity: AA 166-196, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects Uroplakin-1b (UPK1B) (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 166~196 amino acids from the Central region of human UPK1B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: Uroplakin-1b (UPK1B) (UPK1B Products)

Synonyms: MGC81971 antibody, upk1b antibody, MGC81493 antibody, UPK1B antibody, TSPAN20 antibody, UPIB antibody, UPK1 antibody, AI413235 antibody, Tspan20 antibody, UPIb antibody, Upk1 antibody, uroplakin 1B antibody, uroplakin 1B S homeolog antibody, uroplakin 1A S homeolog antibody, UPK1B antibody, upk1b.S antibody, upk1a.S antibody, upk1b antibody, Upk1b antibody

Background: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.Synonyms: TSPAN20, Tetraspanin-20, Tspan-20, UP1b, UPIb, Uroplakin Ib

Gene ID: 7348

NCBI Accession: NP_008883