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ACSL5 antibody (AA 108-683)

This anti-ACSL5 antibody is a Rabbit Polyclonal antibody detecting ACSL5 in WB, ELISA and FACS. Suitable for Human, Rat and Mouse.
Catalog No. ABIN7599690

Quick Overview for ACSL5 antibody (AA 108-683) (ABIN7599690)

Target

See all ACSL5 Antibodies
ACSL5 (Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))

Reactivity

  • 24
  • 8
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse

Host

  • 18
  • 5
  • 1
Rabbit

Clonality

  • 22
  • 2
Polyclonal

Conjugate

  • 20
  • 2
  • 1
  • 1
This ACSL5 antibody is un-conjugated

Application

  • 20
  • 14
  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Binding Specificity

    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 108-683

    Purpose

    Anti-ACSL5 Antibody Picoband®

    Characteristics

    Anti-ACSL5 Antibody Picoband® (ABIN7599690). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human ACSL5 recombinant protein (Position: Y108-D683). Human ACSL5 shares 80.7% and 80.2% amino acid (aa) sequence identity with mouse and rat ACSL5, respectively.
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Al-Thihli, K., Afting, C., Al-Hashmi, N., Mohammed, M., Sliwinski, S., Al Shibli, N., Al-Said, K., Al-Kasbi, G., Al-Kharusi, K., Merle, U., Fullekrug, J., Al-Maawali, A. Deficiency of acyl-CoA synthetase 5 is associated with a severe and treatable failure to thrive of neonatal onset. Clin. Genet. 99: 376-383, 2021. 2. O'Brien, M. J., Beijerink, N. J., Sansom, M., Thornton, S. W., Chew, T., Wade, C. M. A large deletion on CFA28 omitting ACSL5 gene is associated with intestinal lipid malabsorption in the Australian Kelpie dog breed. Sci. Rep. 10: 18223, 2020. 3. Oikawa, E., Iijima, H., Suzuki, T., Sasano, H., Sato, H., Kamataki, A., Nagura, H., Kang, M. J., Fujino, T., Suzuki, H., Yamamoto, T. T. A novel acyl-CoA synthetase, ACS5, expressed in intestinal epithelial cells and proliferating preadipocytes. J. Biochem. 124: 679-685, 1998.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    ACSL5 (Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))

    Alternative Name

    ACSL5

    Background

    Long-chain-fatty-acidoA ligase 5 is an enzyme that in humans is encoded by the ACSL5 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

    Molecular Weight

    76 kDa

    Gene ID

    51703
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