MOSPD2 antibody (AA 111-496)

Catalog No. ABIN7599743

The Rabbit Polyclonal anti-MOSPD2 antibody has been validated for WB, IHC, ELISA and FACS. It is suitable to detect MOSPD2 in samples from Human, Mouse and Rat.

Quick Overview for MOSPD2 antibody (AA 111-496) (ABIN7599743)

Target: MOSPD2 (Motile Sperm Domain Containing 2 (MOSPD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOSPD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-MOSPD2 Antibody

Binding Specificity: AA 111-496

Purpose: Anti-MOSPD2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MOSPD2 Antibody Picoband® (ABIN7599743). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MOSPD2 recombinant protein (Position: R111-Q496).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Di Mattia, T., Martinet, A., Ikhlef, S., McEwen, A. G., Nomine, Y., Wendling, C., Poussin-Courmontagne, P., Voilquin, L., Eberling, P., Ruffenach, F., Cavarelli, J., Slee, J., Levine, T. P., Drin, G., Tomasetto, C., Alpy, F. FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts. EMBO J. 39: e104369, 2020. 2. Di Mattia, T., Wilhelm, L. P., Ikhlef, S., Wendling, C., Spehner, D., Nomine, Y., Giordano, F., Mathelin, C., Drin, G., Tomasetto, C., Alpy, F. Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites. EMBO Rep. 19: e45453, 2018. 3. Mendel, I., Yacov, N., Salem, Y., Propheta-Meiran, O., Ishai, E., Breitbart, E. Identification of motile sperm domain-containing protein 2 as regulator of human monocyte migration. J. Immun. 198: 2125-2132, 2017.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MOSPD2

Target: MOSPD2 (Motile Sperm Domain Containing 2 (MOSPD2))

Alternative Name: MOSPD2

Background:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: MOSPD2 (motile sperm domain-containing protein 2) is a 518 amino acid single-pass membrane protein that contains one CRAL-TRIO domain and a single MSP domain. Existing as two alternatively spliced isoforms, MOSPD2 is encoded by a gene that maps to human chromosome Xp22.2. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner's syndrome, Klinefelter's syndrome and triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Molecular Weight: 60 kDa

Gene ID: 158747