KIAA1045 antibody (AA 113-397)

Catalog No. ABIN7599753

Product Details anti-KIAA1045 Antibody

Target: KIAA1045

Binding Specificity: AA 113-397

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA1045 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-PHF24 Antibody Picoband®

Characteristics: Anti-PHF24 Antibody Picoband® (ABIN7599753). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHF24 recombinant protein (Position: D113-K397). Human PHF24 shares 89.5% amino acid (aa) sequence identity with mouse PHF24.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 6/23/2022. 2. Kikuno, R., Nagase, T., Ishikawa, K., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 197-205, 1999. 3. Miyamoto, K., Yamashita, A., Saito, K. Solution structure of the PHD finger from the human KIAA1045 protein. Protein Sci. 27: 987-992, 2018.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for KIAA1045

Target: KIAA1045

Alternative Name: PHF24 (KIAA1045 Products)

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF24 (PHD finger protein 24), also known as KIAA1045, is a 400 amino acid protein containing one PHD-type zinc finger motif, suggesting involvement in transcriptional regulation events. Conserved in chimpanzee, Rhesus monkey, canine, bovine, mouse, rat, chicken, zebrafish and frog, the gene encoding PHF24 is located on human chromosome 9. Chromosome 9 houses over 900 genes and comprises nearly 4 % of the human genome. Considered to play a role in gender determination, deletion of the distal portion of chromosome 9p can lead to development of male to female sex reversal, the phenotype of a female with a male XY genotype.

Molecular Weight: 45 kDa

Gene ID: 23349