MX1 antibody (AA 116-595)

Catalog No. ABIN7599777

The Rabbit Polyclonal anti-MX1 antibody has been validated for WB, ELISA and FACS. It is suitable to detect MX1 in samples from Human and Mouse.

Quick Overview for MX1 antibody (AA 116-595) (ABIN7599777)

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-MX1 Antibody

Binding Specificity: AA 116-595

Purpose: Anti-MX1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MX1 Antibody Picoband® (ABIN7599777). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MX1 recombinant protein (Position: N116-H595).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bigham, A. W., Buckingham, K. J., Husain, S., Emond, M. J., Bofferding, K. M., Gildersleeve, H., Rutherford, A., Astakhova, N. M., Perelygin, A. A., Busch, M. P., Murray, K. O., Sejvar, J. J., Green, S., Kriesel, J., Brinton, M. A., Bamshad, M. Host genetic risk factors for West Nile virus infection and disease progression. PLoS One 6: e24745, 2011. Note: Electronic Article. 2. Horisberger, M. A., Wathelet, M., Szpirer, J., Szpirer, C., Islam, Q., Levan, G., Huez, G., Content, J. cDNA cloning and assignment to chromosome 21 of IFI-78K gene, the human equivalent of murine Mx gene. Somat. Cell Molec. Genet. 14: 123-131, 1988. 3. Huber, P., Aebi, M., Grob, R., Pravtcheva, D., Ruddle, F., Haller, O. Chromosomal localization of two human Mx genes. (Abstract) Experientia 44: A84 only, 1988.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1

Background:

Synonyms: Complement component C7, C7

Tissue Specificity: Widely expressed.

Background: Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene. This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.

Molecular Weight: 76 kDa

Gene ID: 4599

UniProt: P20591