MX1 antibody (C-Term)

Catalog No. ABIN2782470

This Rabbit Polyclonal antibody specifically detects MX1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit and Sheep.It has been mentioned in 1 publication

Quick Overview for MX1 antibody (C-Term) (ABIN2782470)

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MX1 Antibody

Binding Specificity: C-Term

Purpose: MX1 Antibody - C-terminal region

Sequence: KAMLQLLQDK DTYSWLLKER SDTSDKRKFL KERLARLTQA RRRLAQFPG

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against MX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46077-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MX1 antibody (ABIN2782470)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1

Background:

Background Information: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. MX1 is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

Alternative Symbols: MX, MxA, IFI78, IFI-78K, lncMX1-215

Protein Name: Interferon-induced GTP-binding protein Mx1

Molecular Weight: 75kDa

Gene ID: 4599

NCBI Accession: NP_002453

UniProt: P20591