LRRC1 antibody (AA 120-497)

Catalog No. ABIN7599832

Product Details anti-LRRC1 Antibody

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Binding Specificity: AA 120-497

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-LRRC1 Antibody Picoband®

Characteristics: Anti-LRRC1 Antibody Picoband® (ABIN7599832). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC1 recombinant protein (Position: L120-R497). Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Saito, H., Santoni, M.-J., Arsanto, J.-P., Jaulin-Bastard, F., Le Bivic, A., Marchetto, S., Audebert, S., Isnardon, D., Adelaide, J., Birnbaum, D., Borg, J.-P. Lano, a novel LAP protein ly connected to MAGUK proteins in epithelial cells. J. Biol. Chem. 276: 32051-32055, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for LRRC1

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Alternative Name: LRRC1 (LRRC1 Products)

Background: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.

Molecular Weight: 59 kDa

Gene ID: 55227