Glucuronidase beta antibody (AA 122-575)
Quick Overview for Glucuronidase beta antibody (AA 122-575) (ABIN7599854)
Target
See all Glucuronidase beta (GUSB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 122-575
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Purpose
- Anti-beta glucuronidase/Gusb Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-beta glucuronidase/Gusb Antibody (ABIN7599854). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived mouse beta glucuronidase/Gusb recombinant protein (Position: R122-E575).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))
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Alternative Name
- Gusb
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Background
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Synonyms: Beta-glucuronidase, Gusb, Gus, Gus-s
Background: Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.
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Molecular Weight
- 75 kDa
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Gene ID
- 110006
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UniProt
- P12265
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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