SHKBP1 antibody (AA 129-707)

Catalog No. ABIN7599919

Product Details anti-SHKBP1 Antibody

Target: SHKBP1 (Sh3kbp1 Binding Protein 1 (SHKBP1))

Binding Specificity: AA 129-707

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHKBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: Anti-SHKBP1 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-SHKBP1 Antibody Picoband® (ABIN7599919). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SHKBP1 recombinant protein (Position: Y129-F707). Human SHKBP1 shares 92.1% and 91.4% amino acid (aa) sequence identity with mouse and rat SHKBP1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Feng, L., Wang, J.-T., Jin, H., Qian, K., Geng, J.-G. SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex. Cell Biochem. Funct. 29: 589-596, 2011. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/30/2017. 3. Liu, J.-P., Liu, N.-S., Yuan, H.-Y., Guo, Q., Lu, H., Li, Y.-Y. Human homologue of SETA binding protein 1 interacts with cathepsin B and participates in TNF-induced apoptosis in ovarian cancer cells. Molec. Cell. Biochem. 292: 189-195, 2006.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SHKBP1

Target: SHKBP1 (Sh3kbp1 Binding Protein 1 (SHKBP1))

Alternative Name: SHKBP1 (SHKBP1 Products)

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: SHKBP1 plays a role in lysosomal enzyme-dependent apoptosis and in regulating degradation of activated cell surface receptors.

Molecular Weight: 76 kDa

Gene ID: 92799