TTPA antibody (AA 13-278)

Catalog No. ABIN7599931

Product Details anti-TTPA Antibody

Target: TTPA (Tocopherol (Alpha) Transfer Protein (TTPA))

Binding Specificity: AA 13-278

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-TTPA/TPP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TTPA/TPP1 Antibody Picoband® (ABIN7599931). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTPA/TPP1 recombinant protein (Position: Q13-Q278).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arita, M., Sato, Y., Miyata, A., Tanabe, T., Takahashi, E., Kayden, H. J., Arai, H., Inoue, K. Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. Biochem. J. 306: 437-443, 1995. 2. Cavalier, L., Ouahchi, K., Kayden, H. J., Di Donato, S., Reutenauer, L., Mandel, J.-L., Koenig, M. Ataxia with isolated vitamin E deficiency: heterogeneity of mutations and phenotypic variability in a large number of families. Am. J. Hum. Genet. 62: 301-310, 1998. 3. Cellini, E., Piacentini, S., Nacmias, B., Forleo, P., Tedde, A., Bagnoli, S., Ciantelli, M., Sorbi, S. A family with spinocerebellar ataxia type 8 expansion and vitamin E deficiency ataxia. Arch. Neurol. 59: 1952-1953, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TTPA

Target: TTPA (Tocopherol (Alpha) Transfer Protein (TTPA))

Alternative Name: TTPA (TTPA Products)

Background:

Synonyms: Interleukin-6, IL-6, Il6, Il-6

Tissue Specificity: Expressed in activated macrophages (at protein level).

Background: Alpha-tocopherol transfer protein is a protein that in humans is encoded by the TTPA gene. This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

Molecular Weight: 32 kDa, 37 kDa

Gene ID: 7274

UniProt: P49638