ABRA antibody (AA 13-381)

Catalog No. ABIN7599939

The Rabbit Polyclonal anti-ABRA antibody has been validated for WB and ELISA. It is suitable to detect ABRA in samples from Human, Mouse and Rat.

Quick Overview for ABRA antibody (AA 13-381) (ABIN7599939)

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ABRA Antibody

Binding Specificity: AA 13-381

Purpose: Anti-ABRA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ABRA Antibody Picoband® (ABIN7599939). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ABRA recombinant protein (Position: A13-K381).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arai, A., Spencer, J. A., Olson, E. N. STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription. J. Biol. Chem. 277: 24453-24459, 2002. 2. Kuwahara, K., Barrientos, T., Pipes, G. C. T., Li, S., Olson, E. N. Muscle-specific signaling mechanism that links actin dynamics to serum response factors. Molec. Cell. Biol. 25: 3173-3181, 2005. 3. Kuwahara, K., Teg Pipes, G. C., McAnally, J., Richardson, J. A., Hill, J. A., Bassel-Duby, R., Olson, E. N. Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity. J. Clin. Invest. 117: 1324-1334, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ABRA

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Alternative Name: ABRA

Background:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: Predicted to enable actin binding activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity, positive regulation of Rho protein signal transduction, and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription, DNA-templated and protein import into nucleus. Located in plasma membrane.

Molecular Weight: 39 kDa

Gene ID: 137735

UniProt: Q8N0Z2

Pathways: Protein targeting to Nucleus