NUP155 antibody (AA 133-715)

Catalog No. ABIN7599975

The Rabbit Polyclonal anti-NUP155 antibody has been validated for WB, ELISA, ICC, IF and FACS. It is suitable to detect NUP155 in samples from Human.

Quick Overview for NUP155 antibody (AA 133-715) (ABIN7599975)

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP155 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-NUP155 Antibody

Binding Specificity: AA 133-715

Purpose: Anti-NUP155 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-N Antibody Picoband® (ABIN7599975). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUP155 recombinant protein (Position: D133-K715).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gorlich, D., Mattaj, I. W. Nucleocytoplasmic transport. Science 271: 1513-1518, 1996. 2. Hawryluk-Gara, L. A., Shibuya, E. K., Wozniak, R. W. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Molec. Biol. Cell 16: 2382-2394, 2005. 3. Mitchell, J. M., Mansfeld, J., Capitanio, J., Kutay, U., Wozniak, R. W. Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane. J. Cell Biol. 191: 505-521, 2010.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NUP155

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Alternative Name: NUP155

Background:

Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,

Tissue Specificity: Mostly expressed in brain and liver.

Background: Nucleoporin 155 (Nup155) is a protein that in humans is encoded by the NUP155 gene. Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6.

Molecular Weight: 140-150 kDa

Gene ID: 9631

UniProt: O75694

Pathways: Protein targeting to Nucleus