FGA antibody (AA 139-784)

Catalog No. ABIN7600004

This Rabbit Polyclonal antibody specifically detects FGA in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for FGA antibody (AA 139-784) (ABIN7600004)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-FGA Antibody

Binding Specificity: AA 139-784

Purpose: Anti-Fibrinogen alpha chain/FGA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Fibrinogen alpha chain/FGA Antibody Picoband® (ABIN7600004). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibrinogen alpha chain/FGA recombinant protein (Position: E139-Q784).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahn, H. J., Glickman, J. F., Poon, K. L., Zamolodchikov, D., Jno-Charles, O. C., Norris, E. H., Strickland, S. A novel A-beta-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice. J. Exp. Med. 211: 1049-1062, 2014. 2. Akassoglou, K., Yu, W.-M., Akpinar, P., Strickland, S. Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation. Neuron 33: 861-875, 2002. 3. Alving, B. M., Henschen, A. H. Fibrinogen Giessen I: a congenital homozygously expressed dysfibrinogenemia with A-alpha arg-to-his substitution. Am. J. Hemat. 25: 479-482, 1987.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Alternative Name: FGA

Background:

Synonyms: Fibrinogen alpha chain, FGA

Tissue Specificity: Detected in blood plasma (at protein level).

Background: Fibrinogen alpha chain?is a?protein?that in humans is encoded by the?FGA?gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

Molecular Weight: 95 kDa

Gene ID: 2243

UniProt: P02671