NPFFR2 antibody (AA 14-521)

Catalog No. ABIN7600027

This anti-NPFFR2 antibody is a Rabbit Polyclonal antibody detecting NPFFR2 in WB and ELISA. Suitable for Human.

Quick Overview for NPFFR2 antibody (AA 14-521) (ABIN7600027)

Target: NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPFFR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NPFFR2 Antibody

Binding Specificity: AA 14-521

Purpose: Anti-NPFFR2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NPFFR2 Antibody Picoband® (ABIN7600027). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NPFFR2 recombinant protein (Position: L14-E521).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bonini, J. A., Jones, K. A., Adham, N., Forray, C., Artymyshyn, R., Durkin, M. M., Smith, K. E., Tamm, J. A., Boteju, L. W., Lakhlani, P. P., Raddatz, R., Yao, W.-J., Ogozalek, K. L., Boyle, N., Kouranova, E. V., Quan, Y., Vaysse, P. J, Wetzel, J. M., Branchek, T. A., Gerald, C., Borowsky, B. Identification and characterization of two G protein-coupled receptors for neuropeptide FF. J. Biol. Chem. 275: 39324-39331, 2000. 2. Cikos, S., Gregor, P., Koppel, J. Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. Biochem. Biophys. Res. Commun. 256: 352-356, 1999. 3. Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, T., Pedersen, O., Laakso, M., Arner, P. A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. Am. J. Hum. Genet. 80: 1115-1124, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for NPFFR2

Target: NPFFR2 (NPFF2) (Neuropeptide FF Receptor 2 (NPFF2))

Alternative Name: NPFFR2

Background:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 2,ADAM 2,Cancer/testis antigen 15,CT15,Fertilin subunit beta,PH-30,PH30,PH30-beta,ADAM2,FTNB,

Tissue Specificity: Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.

Background: Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene. This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants.

Molecular Weight: 60 kDa

Gene ID: 10886

UniProt: Q9Y5X5

Pathways: cAMP Metabolic Process