PNPLA1 antibody (AA 141-496)

Catalog No. ABIN7600045

This anti-PNPLA1 antibody is a Rabbit Polyclonal antibody detecting PNPLA1 in ELISA and WB. Suitable for Human.

Quick Overview for PNPLA1 antibody (AA 141-496) (ABIN7600045)

Target: PNPLA1 (Patatin-Like phospholipase Domain Containing 1 (PNPLA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PNPLA1 Antibody

Binding Specificity: AA 141-496

Purpose: Anti-PNPLA1 Antibody Picoband®

Characteristics: Anti-PNPLA1 Antibody Picoband® (ABIN7600045). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PNPLA1 recombinant protein (Position: K141-D496). Human PNPLA1 shares 51.5% amino acid (aa) sequence identity with mouse PNPLA1.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahmad, F., Ansar, M., Mehmood, S., Izoduwa, A., Lee, K., Nasir, A., Abrar, M., Mehmood, S., Ullah, A., Aziz, A., University of Washington Center for Mendelian Genomics, Smith, J. D., Shendure, J., Bamshad, M. J., Nicekrson, D. A., Santos-Cortez, R. L. P., Leal, S. M., Ahmad, W. A novel missense variant in the PNPLA1 gene underlies congenital ichthyosis in three consanguineous families. J. Europ. Acad. Derm. Venereol. 30: e210-e213, 2016. Note: Electronic Article. 2. Boyden, L. M., Craiglow, B. G., Hu, R. H., Zhou, J., Browning, J., Eishenfield, L., Lim, Y. L., Luu, M., Randolph, L. M., Ginarte, M., Fachal, L., Rodriguez-Pazos, L., and 10 others. Phenotypic spectrum of autosomal recessive congenital ichthyosis due to PNPLA1 mutation. Brit. J. Derm. 177: 319-322, 2017. 3. Fachal, L., Rodriguez-Pazos, L., Ginarte, M., Carracedo, A., Toribio, J., Vega, A. Identification of a novel PNPLA1 mutation in a Spanish family with autosomal recessive congenital ichthyosis. (Letter) Brit. J. Derm. 170: 980-982, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for PNPLA1

Target: PNPLA1 (Patatin-Like phospholipase Domain Containing 1 (PNPLA1))

Alternative Name: PNPLA1

Background: PNPLA1 is important in the formation of the epidermal lipid barrier and plays a role in glycerophospholipid metabolism.

Molecular Weight: 58 kDa

Gene ID: 285848

UniProt: Q8N8W4