FXR1 antibody (AA 149-614)

Catalog No. ABIN7600093

This anti-FXR1 antibody is a Rabbit Polyclonal antibody detecting FXR1 in WB, ELISA, IHC, IF, ICC and FACS. Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for FXR1 antibody (AA 149-614) (ABIN7600093)

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-FXR1 Antibody

Binding Specificity: AA 149-614

Purpose: Anti-FXR1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-FXR1 Antibody Picoband® (ABIN7600093). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FXR1 recombinant protein (Position: D149-A614).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bolivar, J., Guelman, S., Iglesias, C., Ortiz, M., Valdivia, M. M. The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. J. Biol. Chem. 273: 17122-17127, 1998. 2. Coy, J. F., Sedlacek, Z., Bachner, D., Hameister, H., Joos, S., Lichter, P., Delius, H., Poustka, A. Highly conserved 3-prime UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum. Molec. Genet. 4: 2209-2218, 1995. 3. Darnell, J. C., Fraser, C. E., Mostovetsky, O., Darnell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for FXR1

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Alternative Name: FXR1

Background:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene. The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 80 kDa

Gene ID: 8087

UniProt: P51114