WDR46 antibody (AA 166-495)

Catalog No. ABIN7600232

Product Details anti-WDR46 Antibody

Target: WDR46 (WD Repeat Domain 46 (WDR46))

Binding Specificity: AA 166-495

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR46 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: Anti-WDR46 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WDR46 Antibody Picoband® (ABIN7600232). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WDR46 recombinant protein (Position: E166-K495).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Herberg, J. A., Beck, S., Trowsdale, J. TAPASIN, DAXX, RGL2, HKE2, and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC. J. Molec. Biol. 277: 839-857, 1998. 2. Rosenberg, S. A., Tong-On, P., Li, Y., Riley, J. P., El-Gamil, M., Parkhurst, M. R., Robbins, P. F. Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy. J. Immun. 168: 2402-2407, 2002. 3. Wada, K., Sato, M., Araki, N., Kumeta, M., Hirai, Y., Takeyasu, K., Furukawa, K., Horigome, T. Dynamics of WD-repeat containing proteins in SSU processome components. Biochem. Cell Biol. 92: 191-199, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for WDR46

Target: WDR46 (WD Repeat Domain 46 (WDR46))

Alternative Name: WDR46 (WDR46 Products)

Background:

Synonyms: Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9, MED9, MED25,

Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Background: WD repeat-containing protein 46 is a protein that in humans is encoded by the WDR46 gene. Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus.

Molecular Weight: 70 kDa

Gene ID: 9277

UniProt: O15213