MTSS1 antibody (AA 17-692)

Catalog No. ABIN7600276

The Rabbit Polyclonal anti-MTSS1 antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect MTSS1 in samples from Human, Mouse and Rat.

Quick Overview for MTSS1 antibody (AA 17-692) (ABIN7600276)

Target: MTSS1 (Metastasis Suppressor 1 (MTSS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTSS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-MTSS1 Antibody

Binding Specificity: AA 17-692

Purpose: Anti-MIM/MTSS1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MIM/MTSS1 Antibody Picoband® (ABIN7600276). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MIM/MTSS1 recombinant protein (Position: Q17-E692).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Callahan, C. A., Ofstad, T., Horng, L., Wang, J. K., Zhen, H. H., Coulombe, P. A., Oro, A. E. MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription. Genes Dev. 18: 2724-2729, 2004. 2. Ishikawa, K., Nagase, T., Nakajima, D., Seki, N., Ohira, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 4: 307-313, 1997. 3. Lee, Y.-G., Macoska, J. A., Korenchuk, S., Pienta, K. J. MIM, a potential metastasis suppressor gene in bladder cancer. Neoplasia 4: 291-294, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MTSS1

Target: MTSS1 (Metastasis Suppressor 1 (MTSS1))

Alternative Name: MTSS1

Background:

Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R

Tissue Specificity: Brain.

Background: Metastasis suppressor protein 1 is a protein that in humans is encoded by the MTSS1 gene. Enables actin monomer binding activity, identical protein binding activity, and signaling receptor binding activity. Predicted to be involved in cellular response to fluid shear stress, negative regulation of epithelial cell proliferation, and urogenital system development. Predicted to act upstream of or within several processes, including actin filament polymerization, adherens junction maintenance, and magnesium ion homeostasis. Located in actin cytoskeleton.

Molecular Weight: 115 kDa

Gene ID: 9788

UniProt: O43312