KRT4 antibody (AA 170-427)
Quick Overview for KRT4 antibody (AA 170-427) (ABIN7600283)
Target
See all KRT4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 170-427
-
Purpose
- Anti-Cytokeratin 4/KRT4 Antibody Picoband®
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
-
Characteristics
- Anti-Cytokeratin 4/KRT4 Antibody Picoband® (ABIN7600283). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human Cytokeratin 4/KRT4 recombinant protein (Position: N170-S427).
-
Isotype
- IgG
-
-
-
-
Application Notes
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R., Peschle, C., Romano, V. Subchromosomal localization of two human cytokeratin genes (KRT4 and KRT15) by in situ hybridization. Cytogenet. Cell Genet. 54: 148-150, 1990. 2. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R. E., Franke, W. W., Peschle, C., Romano, V. Sub-chromosomal localization of human cytokeratin 4, 15, and 19 genes. (Abstract) Cytogenet. Cell Genet. 51: 958 only, 1989. 3. Chao, S.-C., Tsai, Y.-M., Yang, M.-H., Lee, J. Y.-Y. A novel mutation in the keratin 4 gene causing white sponge naevus. Brit. J. Derm. 148: 1125-1128, 2003. -
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- KRT4 (Keratin 4 (KRT4))
-
Alternative Name
- KRT4
-
Background
-
Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,
Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.
Background: Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
-
Molecular Weight
- 56 kDa
-
Gene ID
- 3851
-
UniProt
- P19013
Target
-