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KRT4 antibody (AA 170-427)

This anti-KRT4 antibody is a Rabbit Polyclonal antibody detecting KRT4 in WB, IHC, ELISA and IF. Suitable for Human.
Catalog No. ABIN7600283

Quick Overview for KRT4 antibody (AA 170-427) (ABIN7600283)

Target

See all KRT4 Antibodies
KRT4 (Keratin 4 (KRT4))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This KRT4 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • Binding Specificity

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    AA 170-427

    Purpose

    Anti-Cytokeratin 4/KRT4 Antibody Picoband®

    Cross-Reactivity (Details)

    No cross-reactivity with other proteins.

    Characteristics

    Anti-Cytokeratin 4/KRT4 Antibody Picoband® (ABIN7600283). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Cytokeratin 4/KRT4 recombinant protein (Position: N170-S427).

    Isotype

    IgG
  • Application Notes

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R., Peschle, C., Romano, V. Subchromosomal localization of two human cytokeratin genes (KRT4 and KRT15) by in situ hybridization. Cytogenet. Cell Genet. 54: 148-150, 1990. 2. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R. E., Franke, W. W., Peschle, C., Romano, V. Sub-chromosomal localization of human cytokeratin 4, 15, and 19 genes. (Abstract) Cytogenet. Cell Genet. 51: 958 only, 1989. 3. Chao, S.-C., Tsai, Y.-M., Yang, M.-H., Lee, J. Y.-Y. A novel mutation in the keratin 4 gene causing white sponge naevus. Brit. J. Derm. 148: 1125-1128, 2003.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Storage

    4 °C,-20 °C

    Storage Comment

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    KRT4 (Keratin 4 (KRT4))

    Alternative Name

    KRT4

    Background

    Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,

    Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.

    Background: Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

    Molecular Weight

    56 kDa

    Gene ID

    3851

    UniProt

    P19013
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