PLTP antibody (AA 18-470)

Catalog No. ABIN7600346

This anti-PLTP antibody is a Rabbit Polyclonal antibody detecting PLTP in WB, IHC, ELISA, ICC, FACS and IF. Suitable for Human.

Quick Overview for PLTP antibody (AA 18-470) (ABIN7600346)

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLTP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-PLTP Antibody

Binding Specificity: AA 18-470

Purpose: Anti-PLTP Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PLTP Antibody Picoband® (ABIN7600346). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLTP recombinant protein (Position: E18-E470).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jiang, X., Bruce, C., Mar, J., Lin, M., Ji, Y., Francone, O. L., Tall, A. R. Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-absorbance lipoprotein levels. J. Clin. Invest. 103: 907-914, 1999. 2. Spirin, V., Schmidt, S., Pertsemlidis, A., Cooper, R. S., Cohen, J. C., Sunyaev, S. R. Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-absorbance lipoprotein cholesterol. Am. J. Hum. Genet. 81: 1298-1303, 2007. 3. Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., Johansen, C. T., Fouchier, S. W., and 197 others. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707-713, 2010.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PLTP

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Alternative Name: PLTP

Background:

Synonyms: Protein atonal homolog 1,Class A basic helix-loop-helix protein 14,bHLHa14,Helix-loop-helix protein hATH-1,hATH1,ATOH1,ATH1, BHLHA14,

Tissue Specificity: Retina.

Background: Phospholipid transfer protein (PLTP), also known as lipid transfer protein II is a protein that in humans is encoded by the PLTP gene. This gene is mapped to 20q13.12. The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 65 kDa

Gene ID: 5360

UniProt: P55058

Pathways: Lipid Metabolism