GBP2 antibody (AA 181-589)

Catalog No. ABIN7600364

This anti-GBP2 antibody is a Rabbit Polyclonal antibody detecting GBP2 in WB, ELISA and FACS. Suitable for Mouse.

Quick Overview for GBP2 antibody (AA 181-589) (ABIN7600364)

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-GBP2 Antibody

Binding Specificity: AA 181-589

Purpose: Anti-Gbp2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Gbp2 Antibody Picoband® (ABIN7600364). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Gbp2 recombinant protein (Position: R181-L589).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Cheng, Y.-S. E., Patterson, C. E., Staeheli, P. Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP. Molec. Cell. Biol. 11: 4717-4725, 1991. 2. Kim, B.-H., Shenoy, A. R., Kumar, P., Das, R., Tiwari, S., MacMicking, J. D. A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. Science 332: 717-721, 2011. 3. Olszewski, M. A., Gray, J., Vestal, D. J. In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters. J. Interferon Cytokine Res. 26: 328-352, 2006.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: Gbp2

Background:

Synonyms: Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3, HSPC322

Tissue Specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

Background: Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene. This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.

Molecular Weight: 67 kDa

Gene ID: 14469

UniProt: Q9Z0E6

Pathways: Cellular Response to Molecule of Bacterial Origin