GCM1 antibody (AA 188-436)

Catalog No. ABIN7600391

This anti-GCM1 antibody is a Rabbit Polyclonal antibody detecting GCM1 in WB, ELISA, IF and ICC. Suitable for Human.

Quick Overview for GCM1 antibody (AA 188-436) (ABIN7600391)

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GCM1 Antibody

Binding Specificity: AA 188-436

Purpose: Anti-GCM1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-GCM1 Antibody Picoband® (ABIN7600391). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GCM1 recombinant protein (Position: E188-R436).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Akiyama, Y., Hosoya, T., Poole, A. M., Hotta, Y. The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. Proc. Nat. Acad. Sci. 93: 14912-14916, 1996. 2. Anson-Cartwright, L., Dawson, K., Holmyard, D., Fisher, S. J., Lazzarini, R. A., Cross, J. C. The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta. Nature Genet. 25: 311-314, 2000. 3. Gunther, T., Chen, Z.-F., Kim, J., Priemel, M., Rueger, J. M., Amling, M., Moseley, J. M., Martin, T. J., Anderson, D. J., Karsenty, G. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature 406: 199-203, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GCM1

Target: GCM1 (Glial Cells Missing Homolog 1 (GCM1))

Alternative Name: GCM1

Background:

Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: Chorion-specific transcription factor GCMa is a protein that, in humans, is encoded by the GCM1 gene. This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.

Molecular Weight: 49 kDa

Gene ID: 8521