SYCN antibody (AA 19-134)

Catalog No. ABIN7600400

Product Details anti-SYCN Antibody

Target: SYCN (Syncollin (SYCN))

Binding Specificity: AA 19-134

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCN antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Anti-SYCN Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-SYCN Antibody Picoband® (ABIN7602584). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SYCN recombinant protein (Position: A19-S134). Human SYCN shares 73.9% and 72.2% amino acid (aa) sequence identity with mouse and rat SYCN, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Antonin, W., Wagner, M., Riedel, D., Brose, N., Jahn, R. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Molec. Cell. Biol. 22: 1545-1554, 2002. 2. Bach, J. P., Borta, H., Ackermann, W., Faust, F., Borchers, O., Schrader, M. The secretory granule protein syncollin localizes to HL-60 cells and neutrophils. J. Histochem. Cytochem. 54: 877-888, 2006. 3. Edwardson, J. M., An, S., Jahn, R. The secretory granule protein syncollin binds to syntaxin in a Ca2(+)-sensitive manner. Cell 90: 325-333, 1997.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SYCN

Target: SYCN (Syncollin (SYCN))

Alternative Name: SYCN (SYCN Products)

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: SYCN functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. SYCN may have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.

Molecular Weight: 14 kDa

Gene ID: 342898