CD90 antibody (AA 20-111)

Catalog No. ABIN7600517

This anti-CD90 antibody is a Rabbit Polyclonal antibody detecting CD90 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for CD90 antibody (AA 20-111) (ABIN7600517)

Target: CD90 (THY1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD90 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD90 Antibody

Binding Specificity: AA 20-111

Purpose: Anti-CD90/Thy1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CD90/Thy1 Antibody Picoband® (ABIN7600517). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CD90/Thy1 recombinant protein (Position: Q20-H111).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abeysinghe, H. R., Cao, Q., Xu, J., Pollock, S., Veyberman, Y., Guckert, N. L., Keng, P., Wang, N.THY1 expression is associated with tumor suppression of human ovarian cancer.Cancer Genet. Cytogenet. 143: 125-132, 2003. 2. McKenzie, J. L., Fabre, J. W.Human Thy-1: unusual localization and possible functional significance in lymphoid tissues.J. Immun. 126: 843-850, 1981. 3. Morris, R.Thy-1 in developing nervous tissue.Dev. Neurosci. 7: 133-160, 1985.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CD90

Target: CD90 (THY1)

Alternative Name: THY1

Background:

Synonyms: Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, CD90, THY1

Tissue Specificity: Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297). Detected in the islet of Langerhans (PubMed:21483673).

Background: CD90 (Cluster of Differentiation 90) or Thy-1 is a 25-37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. The CD90 gene is mapped to 11q23.3. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor.

Molecular Weight: 24 kDa

Gene ID: 7070

UniProt: P04216

Pathways: Cell-Cell Junction Organization