MYORG/KIAA1161 antibody (AA 207-611)

Catalog No. ABIN7600584

Product Details anti-MYORG/KIAA1161 Antibody

Target: MYORG/KIAA1161 (MYORG) (Myogenesis Regulating Glycosidase (MYORG))

Binding Specificity: AA 207-611

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYORG/KIAA1161 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Anti-MYORG Antibody Picoband®

Characteristics: Anti-MYORG Antibody Picoband® (ABIN7600584). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYORG recombinant protein (Position: Q207-R611). Human MYORG shares 92.9% amino acid (aa) sequence identity with mouse MYORG.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arkadir, D., Lossos, A., Rahat, D., Snineh, M. A., Schueler-Furman, O., Nitschke, S., Minassian, B. A., Sadaka, Y., Lerer, I., Tabach, Y., Meiner, V. MYORG is associated with recessive primary familial brain calcification. Ann. Clin. Transl. Neurol. 6: 106-113, 2019. 2. Datta, K., Guan, T., Gerace, L. NET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiation. J. Biol. Chem. 284: 29666-29676, 2009. 3. Forouhideh, Y., Muller, K., Ruf, W., Assi, M., Seker, T., Tunca, C., Knehr, A., Strom, T. M., Gorges, M., Schradt, F., Meitinger, T., Ludolph, A. C., Pinkhardt, E. H., Basak, A. N., Kassubek, J., Uttner, I., Weishaupt, J. H. A biallelic mutation links MYORG to autosomal-recessive primary familial brain calcification. (Letter) Brain 142: e4, 2019. Note: Electronic Article.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MYORG/KIAA1161

Target: MYORG/KIAA1161 (MYORG) (Myogenesis Regulating Glycosidase (MYORG))

Alternative Name: MYORG (MYORG Products)

Background: MYORG promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2.

Molecular Weight: 87 kDa

Gene ID: 57462

Pathways: Skeletal Muscle Fiber Development