MANSC1 antibody (AA 21-337)

Catalog No. ABIN7600615

The Rabbit Polyclonal anti-MANSC1 antibody has been validated for WB and ELISA. It is suitable to detect MANSC1 in samples from Human.

Quick Overview for MANSC1 antibody (AA 21-337) (ABIN7600615)

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MANSC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MANSC1 Antibody

Binding Specificity: AA 21-337

Purpose: Anti-MANSC1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MANSC1 Antibody Picoband® (ABIN7600615). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MANSC1 recombinant protein (Position: L21-N337).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clark, H. F. , Gurney, A. L. , Abaya, E. , Baker, K. , Baldwin, D. , & Brush, J. , et al. (2003). The secreted protein discovery initiative (spdi), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Research, 13(10), 2265-2276. 2. Ezh2 depletion potentiates myc degradation inhibiting neuroblastoma and small cell carcinoma tumor formation. Nature Communications. 3. Luck, K. , Kim, D. K. , Lambourne, L. , Spirohn, K. , & Calderwood, M. A. . (2020). A reference map of the human binary protein interactome. Nature, 580(D1).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MANSC1

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Alternative Name: MANSC1

Background:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: MANSC1 (MANSC domain-containing protein 1), also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

Molecular Weight: 62 kDa

Gene ID: 54682

UniProt: Q9H8J5